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ABCD2 is a direct target of beta-catenin and TCF-4: implications for X-linked adrenoleukodystrophy therapy.
Park CY, Kim HS, Jang J, Lee H, Lee JS, Yoo JE, Lee DR, Kim DW. Park CY, et al. PLoS One. 2013;8(2):e56242. doi: 10.1371/journal.pone.0056242. Epub 2013 Feb 21. PLoS One. 2013. PMID: 23437103 Free PMC article.
However, little is known about the transcriptional regulation of ABCD2 gene expression. Here, through in silico analysis, we found two putative TCF-4 binding elements between nucleotide positions -360 and -260 of the promoter region of the ABCD2 gene. ...Moreover, r …
However, little is known about the transcriptional regulation of ABCD2 gene expression. Here, through in silico analysis, we found tw …
Peroxisomal ATP-binding cassette transporters form mainly tetramers.
Geillon F, Gondcaille C, Raas Q, Dias AMM, Pecqueur D, Truntzer C, Lucchi G, Ducoroy P, Falson P, Savary S, Trompier D. Geillon F, et al. J Biol Chem. 2017 Apr 28;292(17):6965-6977. doi: 10.1074/jbc.M116.772806. Epub 2017 Mar 3. J Biol Chem. 2017. PMID: 28258215 Free PMC article.
By using quantitative co-immunoprecipitation assays coupled with tandem mass spectrometry, we identified potential binding partners of ABCD2 involved in polyunsaturated fatty-acid metabolism. Interestingly, we identified calcium ATPases as ABCD2-binding partners, su …
By using quantitative co-immunoprecipitation assays coupled with tandem mass spectrometry, we identified potential binding partners of AB …
Emergence of the Dedifferentiated Phenotype in Hepatocyte-Derived Tumors in Mice: Roles of Oncogene-Induced Epigenetic Alterations.
Watanabe K, Yamamoto M, Xin B, Ooshio T, Goto M, Fujii K, Liu Y, Okada Y, Furukawa H, Nishikawa Y. Watanabe K, et al. Hepatol Commun. 2019 Feb 25;3(5):697-715. doi: 10.1002/hep4.1327. eCollection 2019 May. Hepatol Commun. 2019. PMID: 31061957 Free PMC article.
Hepatocellular carcinoma often reactivates the genes that are transiently expressed in fetal or neonatal livers. ...Although mouse hepatocytes could be transformed by the introduction of HRAS/Myc in vitro, they did not express fetal/neonatal genes and sustained glob …
Hepatocellular carcinoma often reactivates the genes that are transiently expressed in fetal or neonatal livers. ...Although m …
Differential reactivation of fetal/neonatal genes in mouse liver tumors induced in cirrhotic and non-cirrhotic conditions.
Chen X, Yamamoto M, Fujii K, Nagahama Y, Ooshio T, Xin B, Okada Y, Furukawa H, Nishikawa Y. Chen X, et al. Cancer Sci. 2015 Aug;106(8):972-81. doi: 10.1111/cas.12700. Epub 2015 Jun 25. Cancer Sci. 2015. PMID: 26011625 Free PMC article.
Hepatocellular carcinoma develops in either chronically injured or seemingly intact livers. To explore the tumorigenic mechanisms underlying these different conditions, we compared the mRNA expression profiles of mouse hepatocellular tumors induced by the rep …
Hepatocellular carcinoma develops in either chronically injured or seemingly intact livers. To explore the tumorigenic mechani …